Mumaith Khan was born on 1 September 1985. She was born and brought up in Mumbai. Her father is from Pakistan and her mother is from Tiruchirappalli. Khan has acted primarily in Telugu, Hindi, Tamil and Kannada language films. Besides movies, she has appeared in reality shows like Jhalak Dikhla Jaa 6 on Colors TV, Super 2 on ETV Telugu and the first season of Bigg Boss Telugu.
As of 2017 she had worked in 40 Telugu movies, over 20 Hindi movies, 16 Tamil and 5 Kannada films. She received fame with her cameo performance in the Sanjay Dutt starrer Munna Bhai MBBS. Her career was rocked by a controversy of drug allegations in which many south movie stars were also questioned. Her relationship with a prime suspect Calvin Mascerehas was also at the centre of investigation. Because of those allegations, in July 2018, Mumaith was evicted midway from Big Boss Telugu season 1. Later she returned to the reality show after the interrogation.
She made Cameo appearances in noted Telugu films like Swamy, 143, Prabhas' Chatrapati, Mahesh babu's Pokiri, Samanyudu , Bhagyalakshmi Bumper Draw, Operation Duryodhana, Seema Sastri and Bujjigadu. She played the title role in the Telugu film Maisamma IPS in 2007. She appeared in a song in S.S. Rajamouli's Magadheera and in a prominent role in Puri Jagannadh's Neninthe.
In December 2016, Mumaith fell down from the bed at her apartment and hit her head which led to an internal injury damaging her nerves in the brain. She was in a coma for 15 days and the doctors said it would take her two years to recover after treatment and surgery. Subsequently, this led to few neurological health problems like seizures and has been on medication for the last two years. This also led to her gaining weight as her doctor advised her to keep away from the gym. Since then she has been trying to get back in shape gradually and is optimistic of making a comeback.
She was last seen in the Telugu film Tikka that released in 2016, Mumaith is making her comeback with Telugu horror film Heza.